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Case Report: A Report of Tranexamic Acid Ampoule Effect on Uterine Atony After Normal Vaginal Delivery
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Zohreh Mirkazehi1    , Firoze Shekhi1 , , Faride Khavari * 2, Pariya Bamenimoghadam3 |
1- Instructor of Midwifery Department , School of Nursing and Midwifery, Iranshahr University of Medical Sciences, Iranshahr, Iran
2- Instructor of Midwifery Department, School of Nursing and Midwifery, Shahid Soghinejad University of Yazd , Yazd, Iran , midwife_8686@yahoo.com
3- Assistant Professor of Obstetrics and Gynecology, Iranshahr University of Medical Sciences, Iranshahr, Iran |
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Abstract: (2519 Views) |
PPH is one of three main causes of maternal mortality in the developing countries. Atony is responsible for 75-90 % of PPH. In the lack of essential actions for reparation there will be substantial increase of maternal deaths. Recently TXA benefits in reduction of PPH is considered by many researchers. TXA is a finaquinolysis inhibitor. It’s been years TXA is commonly used in surgeries such as coronary artery bypass craft, scoliosis, orthoplasty as well as idiopathic metrorrhagia.
Case Presentation: A 24 years woman G2P1L1 was admitted in Hospital for termination of pregnancy. (GA=40 w+4d) The main complaints were reduction of fetal movements and AFI=6-8cm.Misoprostol inserts for labour induction, after 6 hrs induction continues with oxytocin. By normal delivery baby with normal Apgar score has been born weighing 3100 gr. Placenta and appendix normally delivered. But the uterine was sleazy and atonic. Hemorrhage was +1. Corrugate has been done, there was no remains. Uterotonic agents such as syntosinon, methergine, sublingual misoprostol and two hand uterine massage has been performed. But there was persistently uterine atony and active hemorrhage. Afterwards, finally Amp Tranexamic Acid has been used. Behind 10 minutes of IV injection uterine was well contracted with normal bleeding.
Conclusion: According to literatures and anti fibrinolytic effect of TXA we can use this medicine for resistant atonic uterus. |
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| Keywords: Atony, Tranexamic Acid, PPH |
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Full-Text [PDF 1183 kb]
(829 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2021/07/12 | Accepted: 2021/05/31 | Published: 2021/05/31
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