Background: Several psychological factors known to be involved in Inflammatory Bowl Diseases (IBD) pathology including stress  and stressful life style.The aim of this study was to determine the association between The stress due to job, life health and family in adult diagnosed with IBD referred to Gastroenterology and Hepatology Center, Shariati Hospital in 2014-2015.

Methods: In a case-control analytical research,using Targeted sampling method, eighty individuals as experimental group and eighty individuals as control group participated.

Results: Findings demonstrated the two groups difference regarding means of age, based on Independent-Test (P=0.2) and the difference regarding gender distribution, based on Fishers Exact Test (P= 0.8) were not significant. The two groups difference regarding family stress measured by Independent T -Test, was significant (P 0<001).

Conclusion: Findings showed that these patients had more problems in private life regions like emotional conflicts and relationship with spouse and children than non-patient people.