Volume 5, Issue 1 (1-2016)                   aumj 2016, 5(1): 28-33 | Back to browse issues page


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Jokar A, Tvakoli Sarvestani F, Changizi Ashtiyani S, Zarei A, Ramezani M, Aghababa H. Effect of Omega-3 Fatty Acids on Testosterone Plasma Level in Wistar Rat. aumj 2016; 5 (1) :28-33
URL: http://aums.abzums.ac.ir/article-1-406-en.html
1- Master of Science, Department of Biology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran
2- Associate Professor, Department of Physiology, Arak University of medical sciences. Arak, Iran
3- Young Researchers and Elite Club, Abadeh Branch, Islamic Azad University, Abadeh, Iran
4- Endocrinology and Metabolism research center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
5- Assistant Professor, Department of Biology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran
Abstract:   (8013 Views)

Background and Aims: High prevalence of infertility and many related problems has become a big problem for economy and healthy. This study is to determine the effect of dietary omega-3 based on hypothalamic–pituitary–gonadal axis (HPG) activity and testosterone plasma level in adult male adult wistar rat.

Methods: This experimental study was conducted on 40 adult male wistar rats. Animals were with an average weight of 150±20 gr. They divided into five groups (n=8), including the control group, saline group and experimental group of minimum , average and maximum in which consumed dietary including omega-3, 0.25 and 0.5 and 0.75 mg/kg dose the 29 days. The blood was take from the heart of animals. Using Radioimmunoassay methods, testosterone and LH levels were measured. In this study effects of dietary omega-3 on testosterone secretion level in experimental groups, was compared with saline and control groups.

Results: The results of a compared LH and testosterone level with the control group (0.167±0.02 and 0.182±0.02) and all experimental groups, particularly at the maximum dose (0.654±0.09and 0.584±0.12 respectively), showed a significant increase.

Conclusion: It was shown that the increase in omega-3 plasma levels of in the experimental group led significantly increase in the testosterone and LH level. This study showed that consumption of Omega-3 oils, significantly increase plasma levels of testosterone and LH hormone. 

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Type of Study: Research | Subject: Special
Received: 2016/05/03 | Accepted: 2016/05/03 | Published: 2016/05/03

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