Karimi G, Kabir K, Delpisheh A, Sayehmiri K, Nazari A, Barati H A, et al . Risk Factors for Hepatitis B virus Surface Antigen Positive Prevalence in the Most Migratory Province of Iran: A Matched Case- Control Study. aumj 2015; 4 (1) :17-26
URL:
http://aums.abzums.ac.ir/article-1-266-en.html
1- MSc Student of Epidemiology, Faculty of Health, Student Research Center, Ilam University of Medical Sciences, Ilam, Iran
2- Assistant prof of Community Medicine, Vice Chancellor for Research and Technology ,Alborz University of Medical Sciences, Karaj, Iran
3- Associated Prof of Clinical Epidemiology, Research Center for Prevention of Psycho-Social Injuries, Ilam University of Medical Sciences, Ilam, Iran , alidelpisheh@yahoo.com
4- Associated Prof of Biostatistics, Research Center for Prevention of Psycho-social Injuries, Ilam University of Medical Sciences, Ilam, Iran
5- Assistant Prof & Specialist in Infectious Diseases, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
6- General Practitioner, Director of the Prevention and Combating Disease, Department of Health, Alborz University of Medical Sciences, Karaj, Iran
7- General Practitioner, Savojbolagh Health Center, Savojbolagh Health Care Network, Alborz University of Medical Sciences, Karaj, Iran
8- Expert Disease Control, Department of Health, Alborz University of Medical Sciences, Karaj, Iran
9- BSc of Public Health, Savojbolagh Health center, Savojbolagh Health Care Network, Alborz University of Medical Sciences, Karaj, Iran
Abstract: (7054 Views)
Background and Objective: Hepatitis B Virus Infection is one of the most common infectious diseases and also among the world's top ten causes of this group diseases-related mortality, so that 500,000 to 1.2 million annually die due to the consequences of this infection such as chronic hepatitis, cirrhosis and hepatocellular carcinoma. This study was conducted to determine risk factors for HBsAg-positive prevalence in Alborz Province. Materials and Methods: A 1:1 matched case-control study, 213 of cases reported HBsAg positive to the Alborz University of Medical Sciences in 2013 as case group with 213 of family members of patients with hepatitis C who have serologic markers Anti- HCV negative and HBsAg negative as the control group, were compared in terms of demographic characteristics, History of high risk behaviors, Iatrogenic exposures, community exposures and history of liver disease. Statistical analysis using logistic regression was performed by SPSS software version 18. Results: Reported cases with a mean age of 37.6±15.5 years, was more relevant to marginalized, immigrants and male gender. Nationality, being married, low level of education, family history of HBsAg positive, history of non-intravenous drug abuse, alcohol consumption, history of prison, employment in high risk occupations, sharing of razor, injuries with contaminated sharp instruments and history of jaundice in mother were found to be independent risk factors for HBsAg positive prevalence (OR: 0.27, 3.61, 1.68, 18.04, 12.21, 2.9, 7.52, 2.47, 5.55, 21.48, 11.3, respectively). Conclusions: Unfavorable situation of the marginalized and the prisoners, imported illegal immigrants, especially Afghans can be extended to high-risk behaviors and the threat of a disease surveillance system. Screening and vaccination aforementioned groups, health promotion of the marginalized and raise public knowledge is necessary.
Type of Study:
Research |
Subject:
Special Received: 2015/04/04 | Accepted: 2015/04/04 | Published: 2015/04/04