Volume 13, Issue 4 (Autumn 2024)
aumj 2024, 13(4): 295-299 |
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Noorian S, Saeedi P. An Iranian Adolescent with Disorders of Sex Development: A Case Report of 46,XX Male Disorder and Literature Review. aumj 2024; 13 (4) :295-299
URL: http://aums.abzums.ac.ir/article-1-1809-en.html
URL: http://aums.abzums.ac.ir/article-1-1809-en.html
1- Department of Pediatrics Endocrinology and Metabolisms, Emam Ali Hospital, Alborz University of Medical Sciences and Health Services, Karaj, Iran
2- Faculty of Medicine, Alborz University of Medical Sciences and Health Services, Karaj, Iran ,peysaeidi@gmail.com
2- Faculty of Medicine, Alborz University of Medical Sciences and Health Services, Karaj, Iran ,
Abstract: (598 Views)
The 46,XX male disorder of sexual development is a rare condition, occurring in approximately one in 20,000 live male births. Clinical manifestations can include testicular atrophy, azoospermia, gynecomastia, short stature, cryptorchidism, hypospadias, and micropenis. We present the case of a 13-year-old Iranian boy referred for delayed puberty. Physical examination revealed small testes and micropenis, corresponding to a Tanner stage of G1 for genitalia and P3-4 for pubic hair. Laboratory tests indicated hypergonadotropic hypogonadism, and karyotyping confirmed a 46,XX karyotype. The patient was started on testosterone enanthate at a dosage of 300 mg every three weeks. Additionally, long-term psychological support and regular gonadal monitoring were incorporated into the management plan.
Keywords: Case report Sexual Development Disorders, Testosterone, Puberty Disorders, Karyotype, Hypogonadism.
Type of Study: Case Report |
Subject:
Special
Received: 2024/04/30 | Accepted: 2024/05/11 | Published: 2024/11/30
Received: 2024/04/30 | Accepted: 2024/05/11 | Published: 2024/11/30
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