Volume 13, Issue 2 (Spring 2024)
aumj 2024, 13(2): 77-88 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Moshaverinia M, Manifar S, Fathi Y, Jalouti N. Assessment of the relationship between background factors and quality of life in head and neck cancer patients undergoing radiotherapy in Imam Khomeini hospital in 2023. aumj 2024; 13 (2) :77-88
URL: http://aums.abzums.ac.ir/article-1-1714-en.html
URL: http://aums.abzums.ac.ir/article-1-1714-en.html
1- Asistant Professor, Department of Oral and Maxillofacial Medicine, Alborz University of Medical Science, Karaj, Iran & Asistant Professor, Department of Oral and Maxillofacial Medicine, Alborz University of Medical Science, Karaj, Iran
2- Associate Professor, Department of Oral and Maxillofacial Medicine, Tehran University of Medical Science, Tehran, Iran
3- Oral and Maxillofacial Medicine specialist
4- General Dentist
2- Associate Professor, Department of Oral and Maxillofacial Medicine, Tehran University of Medical Science, Tehran, Iran
3- Oral and Maxillofacial Medicine specialist
4- General Dentist
Abstract: (537 Views)
Background: Oral complications during and after radiotherapy are common and affect the quality of life.This study was aimed to assess the relationship between underlying factors and oral health related quality of life in head and neck cancer patients undergoing radiotherapy.
Methods: This Descriptive-analytical and cross-sectional study was conducted on 85 patients with head and neck cancer referred to the Radiotherapy Center of the Cancer Institute of Imam Khomeini Hospital Complex in Tehran. Sampling was done by "available" sampling method from April to June 2023. Demographic information and information related to the disease were checked in a questionnaire. Also, for the oral health related quality of life, a questionnaire including 26 questions was designed based on the complications and symptoms caused by radiotherapy.
Results: There was no significant relationship between age, gender, education, history of smoking or alcohol consumption, smoking or alcohol consumption at the time of completing the questionnaires, type of lesion, week of the radiotherapy course in which the questionnaire was completed, area of malignant lesion and the quality of life questionnaire score.(P>0.05) There was a significant relationship between occupation, marital status, underlying diseases and the quality of life questionnaire score.(P<0.05)
Conclusion: The results of this article show a general decrease in the quality of life of head and neck cancer patients undergoing radiotherapy. People with a better job status and married people had a higher quality of life, which could be due to better financial and emotional conditions in these people. People with underlying diseases also reported a higher quality of life, which could be due to getting used to the conditions of the disease and starting radiotherapy with a lower quality of life. These results can help in better implementation of care and in providing necessary support for these people.
Methods: This Descriptive-analytical and cross-sectional study was conducted on 85 patients with head and neck cancer referred to the Radiotherapy Center of the Cancer Institute of Imam Khomeini Hospital Complex in Tehran. Sampling was done by "available" sampling method from April to June 2023. Demographic information and information related to the disease were checked in a questionnaire. Also, for the oral health related quality of life, a questionnaire including 26 questions was designed based on the complications and symptoms caused by radiotherapy.
Results: There was no significant relationship between age, gender, education, history of smoking or alcohol consumption, smoking or alcohol consumption at the time of completing the questionnaires, type of lesion, week of the radiotherapy course in which the questionnaire was completed, area of malignant lesion and the quality of life questionnaire score.(P>0.05) There was a significant relationship between occupation, marital status, underlying diseases and the quality of life questionnaire score.(P<0.05)
Conclusion: The results of this article show a general decrease in the quality of life of head and neck cancer patients undergoing radiotherapy. People with a better job status and married people had a higher quality of life, which could be due to better financial and emotional conditions in these people. People with underlying diseases also reported a higher quality of life, which could be due to getting used to the conditions of the disease and starting radiotherapy with a lower quality of life. These results can help in better implementation of care and in providing necessary support for these people.
Type of Study: Research |
Subject:
Special
Received: 2023/09/04 | Accepted: 2023/10/17 | Published: 2024/06/01
Received: 2023/09/04 | Accepted: 2023/10/17 | Published: 2024/06/01
References
1. Vigneswaran N, Williams MD. Epidemiologic trends in head and neck cancer and aids in diagnosis. Oral Maxillofac Surg Clin North Am 2014;26(2): 123-41. [DOI:10.1016/j.coms.2014.01.001]
2. Tranby EP, Heaton LJ, Tomar SL, et al. Oral Cancer Prevalence, Mortality, and Costs in Medicaid and Commercial Insurance Claims Data. Cancer Epidemiol Biomarkers Prev 2022;31(9): 1849-57. [DOI:10.1158/1055-9965.EPI-22-0114]
3. Chow LQM. Head and Neck Cancer. New England Journal of Medicine 2020;382(1): 60-72. [DOI:10.1056/NEJMra1715715]
4. Son E, Panwar A, Mosher CH, Lydiatt D. Cancers of the Major Salivary Gland. J Oncol Pract 2018;14(2): 99-108. [DOI:10.1200/JOP.2017.026856]
5. Gandini S, Botteri E, Iodice S, et al. Tobacco smoking and cancer: a meta-analysis. Int J Cancer 2008;122(1): 155-64. [DOI:10.1002/ijc.23033]
6. Hashibe M, Brennan P, Benhamou S, et al. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. J Natl Cancer Inst 2007;99(10): 777-89. [DOI:10.1093/jnci/djk179]
7. Gillison ML, D'Souza G, Westra W, et al. Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J Natl Cancer Inst 2008;100(6): 407-20. [DOI:10.1093/jnci/djn025]
8. Horn-Ross PL, Ljung BM, Morrow M. Environmental factors and the risk of salivary gland cancer. Epidemiology 1997;8(4): 414-9. [DOI:10.1097/00001648-199707000-00011]
9. Ho PS, Ko YC, Yang YH, et al. The incidence of oropharyngeal cancer in Taiwan: an endemic betel quid chewing area. J Oral Pathol Med 2002;31(4): 213-9. [DOI:10.1034/j.1600-0714.2002.310404.x]
10. Boffetta P, Richiardi L, Berrino F, et al. Occupation and larynx and hypopharynx cancer: an international case-control study in France, Italy, Spain, and Switzerland. Cancer Causes Control 2003;14(3): 203-12. [DOI:10.1023/A:1023699717598]
11. Chien YC, Chen JY, Liu MY, et al. Serologic markers of Epstein-Barr virus infection and nasopharyngeal carcinoma in Taiwanese men. N Engl J Med 2001;345(26): 1877-82. [DOI:10.1056/NEJMoa011610]
12. Beddok A, Krieger S, Castera L, et al. Management of Fanconi Anemia patients with head and neck carcinoma: Diagnosis and treatment adaptation. Oral Oncol 2020;108: 104816. [DOI:10.1016/j.oraloncology.2020.104816]
13. Yu MC, Yuan JM. Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 2002;12(6): 421-9. [DOI:10.1016/S1044579X02000858]
14. Owens D, Paleri V, Jones AV. Head and neck cancer explained: an overview of management pathways. British Dental Journal 2022;233(9): 721-5. [DOI:10.1038/s41415-022-5199-1]
15. Rhee JS, Matthews BA, Neuburg M, et al. The skin cancer index: clinical responsiveness and predictors of quality of life. The Laryngoscope 2007;117(3): 399-405. [DOI:10.1097/MLG.0b013e31802e2d88]
16. Brook I. Late side effects of radiation treatment for head and neck cancer. Radiat Oncol J 2020;38(2): 84-92. [DOI:10.3857/roj.2020.00213]
17. Brook I. Early side effects of radiation treatment for head and neck cancer. Cancer Radiother 2021;25(5): 507-13. [DOI:10.1016/j.canrad.2021.02.001]
18. Liao L-J, Hsu W-L, Lo W-C, et al. Health-related quality of life and utility in head and neck cancer survivors. BMC cancer 2019;19(1): 1-10. [DOI:10.1186/s12885-019-5614-4]
19. Terrell JE, Ronis DL, Fowler KE, et al. Clinical predictors of quality of life in patients with head and neck cancer. Archives of Otolaryngology-Head & Neck Surgery 2004;130(4): 401-8. [DOI:10.1001/archotol.130.4.401]
20. Sharma Y, Mishra G, Parikh V. Quality of life in head and neck cancer patients. Indian Journal of Otolaryngology and Head & Neck Surgery 2019;71: 927-32. [DOI:10.1007/s12070-019-01620-2]
21. Oozeer NB, Benbow J, Downs C, et al. The effect of comorbidity on quality of life during radiotherapy in head and neck cancer. Otolaryngology-Head and Neck Surgery 2008;139(2): 268-72. [DOI:10.1016/j.otohns.2008.05.027]
22. wayne w. daniel aM. principles and methods of biostatistics. 10 ed. iran: amirkabir; 2013.
23. Singer S, Amdal C, Hammerlid E, et al. EORTC Quality of Life and the EORTC Head and Neck Cancer Groups. International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV. Head Neck 2019;41(6): 1725-37. [DOI:10.1002/hed.25609]
24. cancer teofrato. EORTC QLQ-H&N43 2015 [cited 2023 february 20]. Available from: https://qol.eortc.org/questionnaire/qlq-hn43/.
25. Lo P, Lo SK, Tong M, et al. Quality-of-life measurement in patients undergoing radiation therapy for head and neck cancer: a Hong Kong experience. The Journal of oncology management: the official journal of the American College of Oncology Administrators 2004;13(6): 13-23.
26. Onakoya PA, Nwaorgu OG, Adenipekun AO, et al. Quality of life in patients with head and neck cancers. Journal of the National Medical Association 2006;98(5): 765.
27. Bhardwaj T. Quality of life of head and neck cancer patients: Psychosocial perspective using mixed method approach. Indian Journal of Palliative Care 2021;27(2): 291. [DOI:10.25259/IJPC_108_21]
28. Fang F-M, Chien C-Y, Kuo S-C, et al. Changes in quality of life of head-and-neck cancer patients following postoperative radiotherapy. Acta Oncologica 2004;43(6): 571-8. [DOI:10.1080/02841860410018430]
29. Demiral AN, Şen M, Demiral Y, Kınay M. The effect of socioeconomic factors on quality of life after treatment in patients with head and neck cancer. International Journal of Radiation Oncology* Biology* Physics 2008;70(1): 23-7. [DOI:10.1016/j.ijrobp.2007.05.056]
30. Lin A, Kim HM, Terrell JE, et al. Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study. International Journal of Radiation Oncology* Biology* Physics 2003;57(1): 61-70. [DOI:10.1016/S0360-3016(03)00361-4]
31. Duffy SA, Ronis DL, Valenstein M, et al. Depressive symptoms, smoking, drinking, and quality of life among head and neck cancer patients. Psychosomatics 2007;48(2): 142-8. [DOI:10.1176/appi.psy.48.2.142]
32. Allison PJ. Alcohol consumption is associated with improved health-related quality of life in head and neck cancer patients. Oral Oncol 2002;38(1): 81-6. [DOI:10.1016/S1368-8375(01)00031-8]
33. Klein J, Livergant J, Ringash J. Health related quality of life in head and neck cancer treated with radiation therapy with or without chemotherapy: a systematic review. Oral oncology 2014;50(4): 254-62. [DOI:10.1016/j.oraloncology.2014.01.015]
34. Østhus AA, Aarstad AK, Olofsson J, Aarstad HJ. Comorbidity is an independent predictor of health-related quality of life in a longitudinal cohort of head and neck cancer patients. European Archives of Oto-Rhino-Laryngology 2013;270: 1721-8. [DOI:10.1007/s00405-012-2207-0]
35. Heutte N, Plisson L, Lange M, et al. Quality of life tools in head and neck oncology. European Annals of Otorhinolaryngology, Head and Neck Diseases 2014;131(1): 33-47. [DOI:10.1016/j.anorl.2013.05.002]
36. Hammerlid E, Taft C. Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms. British journal of cancer 2001;84(2): 149-56. [DOI:10.1054/bjoc.2000.1576]
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
