Volume 12, Issue 2 (Spring 2023)
aumj 2023, 12(2): 109-115 |
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Mehrpour tarhani F, Ramezani M, Almasi A, Hematti M, Amirian F. Epidemiologic survey and clinic-pathologic assessment of endometrial cancer in Kermanshah during 2013-2018. aumj 2023; 12 (2) :109-115
URL: http://aums.abzums.ac.ir/article-1-1699-en.html
URL: http://aums.abzums.ac.ir/article-1-1699-en.html
Fatemeh Mehrpour tarhani1 
, Mazaher Ramezani *2 , Afshin Almasi3 , Maryam Hematti4 , Farhad Amirian5
, Mazaher Ramezani *2 , Afshin Almasi3 , Maryam Hematti4 , Farhad Amirian5
1- General Practitioner, Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran-Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
2- Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran-Associate Professor of Dermatopathology, Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
3- Assisstant Professor of Biostatistics, Clinical Research Development Center, Imam Khomeini, Mohammad Kermanshahi, Farabi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
4- Master of Statistics, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
5- Pathologist, Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
2- Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran-Associate Professor of Dermatopathology, Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
3- Assisstant Professor of Biostatistics, Clinical Research Development Center, Imam Khomeini, Mohammad Kermanshahi, Farabi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
4- Master of Statistics, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
5- Pathologist, Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
Abstract: (726 Views)
Background: Endometrial cancer is the most common gynecological cancer and accounts for six percent of malignancies in women. The aim of this study was evaluation of epidemiology of this cancer and clinico-pathologic characteristics of patients in west of Iran.
Materials and Methods: Forty four patients with endometrial malignancy referred to Imam Reza hospital in Kermanshah were included in this descriptive-cross sectional study. Data was extracted from archive files and pathology reports in the hospital.
Results: The mean age of patients was 56.95+/_ 11.31 years and the majority were in the age range of 50-60 years. None of the patients had a history of tamoxifen therapy, oligomenorrhea, late menopause and premature menarche, infertility or alcohol use. The majority of patients had no family history of endometrial cancer (90.9%). A family history of endometrial adenocarcinoma was observed in only 4 patients. Endometrial adenocarcinoma (88.6%) and endometrial stromal sarcoma (11.4%) were the most common endometrial cancers in patients, respectively. Vaginal bleeding was reported as the most common clinical symptom in the majority of patients. The age distribution of patients showed that patients under the age of 60 years and also more than 60 years are mostly diagnosed with endometrial adenocarcinoma.
Conclusion: Endometrial adenocarcinoma is the most common endometrial malignancy in west of Iran, that mainly is presented in the sixth decade with vaginal bleeding. This cancer showed no obvious association with known risk factors in west of Iran.
Materials and Methods: Forty four patients with endometrial malignancy referred to Imam Reza hospital in Kermanshah were included in this descriptive-cross sectional study. Data was extracted from archive files and pathology reports in the hospital.
Results: The mean age of patients was 56.95+/_ 11.31 years and the majority were in the age range of 50-60 years. None of the patients had a history of tamoxifen therapy, oligomenorrhea, late menopause and premature menarche, infertility or alcohol use. The majority of patients had no family history of endometrial cancer (90.9%). A family history of endometrial adenocarcinoma was observed in only 4 patients. Endometrial adenocarcinoma (88.6%) and endometrial stromal sarcoma (11.4%) were the most common endometrial cancers in patients, respectively. Vaginal bleeding was reported as the most common clinical symptom in the majority of patients. The age distribution of patients showed that patients under the age of 60 years and also more than 60 years are mostly diagnosed with endometrial adenocarcinoma.
Conclusion: Endometrial adenocarcinoma is the most common endometrial malignancy in west of Iran, that mainly is presented in the sixth decade with vaginal bleeding. This cancer showed no obvious association with known risk factors in west of Iran.
Type of Study: Research |
Subject:
Special
Received: 2022/05/16 | Accepted: 2023/03/06 | Published: 2023/05/31
Received: 2022/05/16 | Accepted: 2023/03/06 | Published: 2023/05/31
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