[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 8, Issue 1 (2-2019) ::
aumj 2019, 8(1): 61-68 Back to browse issues page
The Effects of Probiotics on Indirect Bilirubin Level in the Infants with Neonatal Jaundice
Mohammad Golshan Tafti , Faezeh Eftekhari , Ahmad Shajari , Eyed Mohammad Amin Hashemipour
Assistant Professor, Neonatal Specialty, Faculty of Medicine Ali ibn Abitaleb (AS), Islamic Azad University, Yazd Branch, Iran , mgolshan035@gmail.com
Abstract:   (27 Views)
Objective: At the beginning of the birth, due to an increase in enterohepatic cycle, the baby is at high risk for jaundice, leading to a physiologic jaundice. Although phototherapy is a safe treatment, it can lead to complications such as hyperthermia, erythematous rashes, inflammatory fluids, and diarrhea. Thus, a new therapeutic approach to lowering the level of bilirubin and also reducing the need for phototherapy can be According to the studies, probiotics (pedilact) regulate intestinal function of the enterohepatic vasculature and therefore may be effective in the treatment of neonatal hyperbilirubinemia. The aim of this study was to investigate the effect of probiotics on indirect indirect bilirubin levels in the blood.
Material and Methods: This analytical study was carried out using clinical parallels and parallelism with B & A design the study population consisted of 80 neonates with Hyperbilirubinemia who were randomly divided into two groups of exposed and non-invasive subjects. Non-existent group members were treated with phototherapy only and the newborns in the exposure group received 5 drops of probiotics daily for discharge until they were received. Data were analyzed using SPSS 17 software and independent t-test, paired t-test and ANOVA
Results: The mean of indirect bilirubin reduction on the first day was 3.4 mg / dl in the phototherapy group and 3.5 mg / dl in the phototherapy + probiotic group and was not significant with p-value of 949.0. The mean of indirect bilirubin reduction per day The second one was 6.3 mg / dl in the phototherapy group and 7.mg / dl in the phototherapy + probiotic group, which was more than the phototherapy group and had no significance with p-value = 0.177. Indirect bilirubin reduction on day 3 of the phototherapy group / 6mg / dl in the phototherapy + probiotic group was 7.1 mg / dl, which is more than phototherapy group and does not have significant significance with p-value=0.618.
Conclusion: The mean of bilirubin reduction in the phototherapy + probiotic group is slightly higher than that in the phototherapy group but is not statistically significant.
Keywords: Probiotics, Neonatal Jaundice, Indirect Bilirubin Reduction
Full-Text [PDF 262 kb]   (31 Downloads)    
Type of Study: Research | Subject: Special
Received: 2019/03/08 | Accepted: 2019/03/08 | Published: 2019/03/08
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Golshan Tafti M, Eftekhari F, Shajari A, Hashemipour E M A. The Effects of Probiotics on Indirect Bilirubin Level in the Infants with Neonatal Jaundice. aumj. 2019; 8 (1) :61-68
URL: http://aums.abzums.ac.ir/article-1-887-en.html


Volume 8, Issue 1 (2-2019) Back to browse issues page
نشریه دانشگاه علوم پزشکی البرز Alborz University Medical Journal
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 3855