[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
site facilities::
Indexing::
open access policy::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE

..
:: Volume 4, Issue 2 (5-2015) ::
aumj 2015, 4(2): 129-136 Back to browse issues page
The Synthesis and Characterization of Magnetic Nano Gold and Their Application for Antibody Immobilization
A. Ahmadi , N. Zarghami , H. Shirazi , N. Poorbagher , K. Omidfar
Endocrinology research center,Tehran University of Medical Sciences,Iran , omidfar@tums.ac.ir
Abstract:   (9095 Views)

Background: Gold (Au) Fe oxide core-shell nanostructure is a major class of nanoscale material that has attracted a considerable attention due to the biotechnological and biomedical applications and specific properties. Methods: Here we synthesized the magnetite nanoparticles (MNPs) with an average size of 10-12 nm in diameter using the chemical co-precipitation of Fe2+ and Fe3+ in strong alkaline material. Then, an Au coated Fe oxide core-shell nanocomposite with an average diameter of 18-20 nm was produced in the presence of sodium citrate as the reducing agent. The structures of Au shell and magnetic core (Au–Fe oxide) were studied by transmission electron microscopy (TEM), X-ray diffraction (XRD) and fourier transformed infrared spectroscopy (FTIR). Results: Results showed that the NPs were agglomerate-free and shaped regularly, with a narrow sized distribution. The Au-coated Fe oxide NPs exhibited a surface plasmon resonance peak in the range of 500-650 nm with a remarkable peak at 550 nm. Conclusions: Immobilization studies with antibody (Ab) demonstrated that the Au Fe oxide core-shell nanostructure can be used to immobilize Ab, making them valuable for biomedical and biological applications.

Keywords: Antibody, Au Fe oxide NPs, Core-shell nanocomposite, Immobilization
Full-Text [PDF 302 kb]   (3172 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/08/04 | Accepted: 2015/08/04 | Published: 2015/08/04
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

ahmadi A, zarghami N, shirazi H, poorbagher N, omidfar K. The Synthesis and Characterization of Magnetic Nano Gold and Their Application for Antibody Immobilization. aumj 2015; 4 (2) :129-136
URL: http://aums.abzums.ac.ir/article-1-313-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 4, Issue 2 (5-2015) Back to browse issues page
نشریه دانشگاه علوم پزشکی البرز Alborz University Medical Journal
Persian site map - English site map - Created in 0.06 seconds with 39 queries by YEKTAWEB 4645