دوره 14، شماره 3 - ( تابستان 1404 1404 )                   جلد 14 شماره 3 صفحات 312-301 | برگشت به فهرست نسخه ها

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Mansouri F. An overview of gene transfer technology using nanotechnology in the diagnosis and treatment of diseases. aumj 2025; 14 (3) :301-312
URL: http://aums.abzums.ac.ir/article-1-1843-fa.html
منصوری فاطمه. مروری بر تکنولوژی انتقال ژن با استفاده از نانوتکنولوژی در تشخیص و درمان بیماریها. نشریه علمی پژوهشی دانشگاه علوم پزشکی البرز. 1404; 14 (3) :301-312

URL: http://aums.abzums.ac.ir/article-1-1843-fa.html

مروری بر تکنولوژی انتقال ژن با استفاده از نانوتکنولوژی در تشخیص و درمان بیماریها
فاطمه منصوری*
گروه ژنتیک و ایمونولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران ، mansouri1600@hotmail.com
چکیده:   (495 مشاهده)
مقدمه: امروزه روشهای مختلفی برای انتقال ژن ها و داروها در تشخیص و درمان بر اساس نوع بیماری استفاده میشود. نانو ذرات متنوعی امروزه در دسترس هستند. در این مقاله استفاده از نانو ذرات و انواع ان در انتقال داروها و ژنها در بیماریهای مختلف مورد بررسی قرار می گیرد.
روش کار:  در این مطالعه مروری، جستجوی اولیه در پایگاههایPubMed, Ovid, Google Scholar  و Web of Science  انجام شد. دو هزار مقاله اصیل و مروری به زبان انگلیسی دارای متن کامل با روش تحلیل محتوای مستقیم انتخاب شدند. از بین آنها یکصد مقاله مورد مطالعه و بررسی نهایی قرار گرفت.
یافته ها: یافته ها نشان میدهد که از نانوذرات در انتقال ژن و دارو، تشخیص سریعتر تومور و همچنین انتقال هدفمند دارو با عوارض جانبی کم‌تر میتوان استفاده کرد.  استفاده از انواع سیستمهای نانویی در بهبود روند بیماری، افزایش سرعت تشخیص، کاهش سمیت داروها، افزایش اثرات داروها در درمان سرطان‌ها و بیماریهای مختلف کاربرد زیادی دارد.
نتیجه گیری: توسعه فناوری نانو می تواند منجر به درمان های دقیق، هدفمند و تشخیص سریعتر انواع بیماریها‌ گردد.

واژه‌های کلیدی: نانوذرات، انتقال دارو، انتقال ژن، تشخیص تومور، دارورسانی هدفمند
متن کامل [PDF 800 kb]   (128 دریافت)    
نوع مطالعه: پژوهشی کاربردی | موضوع مقاله: عمومى
دریافت: 1403/6/6 | پذیرش: 1404/1/5 | انتشار: 1404/3/4
فهرست منابع
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