Volume 14, Issue 1 (Winter 2025)
aumj 2025, 14(1): 49-58 |
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Ziaee M, Ahmadi R, Khajavi A, Moadel A, Sharifi Mood F, Tavakolizadeh M. Prevalence and Pattern of Nosocomial Infections in a Hospital in North East of Iran during 2017-2021. aumj 2025; 14 (1) :49-58
URL: http://aums.abzums.ac.ir/article-1-1716-en.html
URL: http://aums.abzums.ac.ir/article-1-1716-en.html
Prevalence and Pattern of Nosocomial Infections in a Hospital in North East of Iran during 2017-2021
Maliheh Ziaee1 
, Reza Ahmadi1 , Abdoljavad Khajavi1 , Alireza Moadel1 , Farnoosh Sharifi Mood1 , Mitra Tavakolizadeh *2
, Reza Ahmadi1 , Abdoljavad Khajavi1 , Alireza Moadel1 , Farnoosh Sharifi Mood1 , Mitra Tavakolizadeh *2
1- Gonabad University of Medical Sciences, Gonabad, Iran
2- Gonabad University of Medical Sciences, Gonabad, Iran ,tavakolizadeh.m@gmu.ac.ir
2- Gonabad University of Medical Sciences, Gonabad, Iran ,
Abstract: (1000 Views)
Background: Nosocomial infections represent a significant healthcare challenge worldwide, leading to increased treatment costs, extended hospital stays, and higher mortality rates. Effective control of these infections is essential for improving patient health and reducing healthcare expenses. This study aimed to determine the prevalence of nosocomial infections at a hospital in northeastern Iran from 2017 to 2021.
Methods: In this cross-sectional descriptive-analytical study, data were collected for 574 patients with nosocomial infections hospitalized in the selected hospital during the specified period. This information was extracted from the national nosocomial infection surveillance system and analyzed using SPSS v25 with appropriate statistical tests, considering a significance level of p<0.05.
Results: The overall prevalence of nosocomial infections during the study period was 0.76%. The mean age of affected patients was 60.25±34.37 years, with an average time of 14.67±28.32 days between admission and infection, and a mean length of stay of 29.02±31.15 days. Women represented 55.6% of the cases, with the highest prevalence recorded in 2021 at 36.7%. The most commonly identified pathogens were "Staphylococcus aureus" and "Escherichia coli". Tracheal tube and urine samples were the most frequently tested specimens.
Conclusion: The study highlights a higher prevalence of nosocomial infections in intensive care units and internal wards, particularly among patients with tracheal tubes and urinary catheters. These findings emphasize the need for implementing targeted preventive measures to mitigate the risk of nosocomial infections in hospital settings.
Methods: In this cross-sectional descriptive-analytical study, data were collected for 574 patients with nosocomial infections hospitalized in the selected hospital during the specified period. This information was extracted from the national nosocomial infection surveillance system and analyzed using SPSS v25 with appropriate statistical tests, considering a significance level of p<0.05.
Results: The overall prevalence of nosocomial infections during the study period was 0.76%. The mean age of affected patients was 60.25±34.37 years, with an average time of 14.67±28.32 days between admission and infection, and a mean length of stay of 29.02±31.15 days. Women represented 55.6% of the cases, with the highest prevalence recorded in 2021 at 36.7%. The most commonly identified pathogens were "Staphylococcus aureus" and "Escherichia coli". Tracheal tube and urine samples were the most frequently tested specimens.
Conclusion: The study highlights a higher prevalence of nosocomial infections in intensive care units and internal wards, particularly among patients with tracheal tubes and urinary catheters. These findings emphasize the need for implementing targeted preventive measures to mitigate the risk of nosocomial infections in hospital settings.
Keywords: Nosocomial Infections, Prevalence, Intensive Care Units, Staphylococcus aureus, Escherichia coli
Type of Study: Research |
Subject:
Special
Received: 2023/09/10 | Accepted: 2024/05/25 | Published: 2024/12/30
Received: 2023/09/10 | Accepted: 2024/05/25 | Published: 2024/12/30
References
1. Rahmanian vahid, Shakeri H, Shakeri M, Rahmanian K, Rahimi M. Epidemiology of nosocomial infections in patients admitted in hospitals Jahrom -2016. jumsjmj [Internet]. 2017 May 1;15(1):57-66. Available from: http://jmj.jums.ac.ir/article-1-986-fa.html [DOI:10.29252/jmj.15.1.57]
2. Ma'somi-Asl HZM, Majidpour A, Nategian AR, Afhami SH, Rahbar M. National guideline of nosocomial infections surveillance. Tehran: Iran Ministry of Health and Educational Medicine: Center for Disease …; 2007.
3. Kallel H, Bahoul M, Ksibi H, Dammak H, Chelly H, Hamida C Ben, et al. Prevalence of hospital-acquired infection in a Tunisian hospital. J Hosp Infect. 2005;59(4):343-7. [DOI:10.1016/j.jhin.2004.09.015] [PMID]
4. Bijari B, Abbasi A, Hemati M, Karabi K. Nosocomial infections and related factors in southern khorasan hospitals. Iran J Med Microbiol. 2015;8(4):69-73.
5. Alberti C, Brun-Buisson C, Burchardi H, Martin C, Goodman S, Artigas A, et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med. 2002;28(2):108-21. [DOI:10.1007/s00134-001-1143-z] [PMID]
6. Spencer RC. Mandell, Douglas and Bennett's Principles and Practice of Infectious Disease 5th edn (two volumes). J Antimicrob Chemother. 2000;46(2):343. [DOI:10.1093/jac/46.2.343]
7. Garcia R. A review of the possible role of oral and dental colonization on the occurrence of health care-associated pneumonia: underappreciated risk and a call for interventions. Am J Infect Control. 2005;33(9):527-41. [DOI:10.1016/j.ajic.2005.02.005] [PMID]
8. Lee MK, Chiu CS, Chow VC, Lam RK, Lai RW. Prevalence of hospital infection and antibiotic use at a university medical center in Hong Kong. J Hosp Infect. 2007;65(4):341-7. [DOI:10.1016/j.jhin.2006.12.013] [PMID] []
9. Ghorban AM, Rangbar R, Joneydi JNA, Esfahani AA, Esmaeili D, Goudarzi Z. A study on the prevalence of nosocomial infections in ICU patients admitted at Baqyiatallah Hospital. Journal Of Ilam University Of Medical Science. 2008:1-16. [In Persian]. 2008;
10. Reed D, Kemmerly SA. Infection control and prevention: a review of hospital-acquired infections and the economic implications. Ochsner J. 2009;9(1):27-31.
11. Emori TG, Culver DH, Horan TC, Jarvis WR, White JW, Olson DR, et al. National nosocomial infections surveillance system (NNIS): description of surveillance methods. Am J Infect Control. 1991;19(1):19-35. [DOI:10.1016/0196-6553(91)90157-8] [PMID]
12. Asl HM, Ed. Epidemiologic study of nosocomial infections in children under 15years old admitted to Hazrat Rasool Akram Hospital using standard NNIS method in the second half of 2002. Tehran: Medicine Faculty of Iran Uni Med Sci; 2002. [In Persian].
13. Barak M, Pourfarzi F, Jirodi Sh, Rahimi G, Pahlavan Y. Etiology and Clinical Investigation of Nosocomial Infections at Ardabil Bou-Ali Hospital during 2010. J Ardabil Univ Med Sci 2012;12:33-39. [In Persian].
14. Noori NM, Meraji SM, Mahjoubi Fard M. Cardiac surgery and hospital infection in intensive care units of Shahid Rajaie Heart Hospital. Journal of Iranian Society of Anesthesiology and Intensive Care 2007;59:63-70. [In Persian].
15. Bahrami M, Pouryousef A, Abbasian S, Eelbeigi Z, Faramarzi A. Survey of the prevalence of nosocomial infections and Antibiotic Sensitivity and resistance in 9 Dey Hospital in Torbat heydareh between 2013-2016. Beyhagh [Internet]. 2018;23(4):10-21. Available from: http://beyhagh.medsab.ac.ir/article_1206.html
16. Mazzeffi M, Gammie J, Taylor B, Cardillo S, Haldane-Lutterodt N, Amoroso A, et al. Healthcare-Associated Infections in Cardiac Surgery Patients With Prolonged Intensive Care Unit Stay. Ann Thorac Surg 2017;103:1161170. [DOI:10.1016/j.athoracsur.2016.12.041] [PMID]
17. Larypoor M, Frsad S. Evaluation of nosocomial infections in one of hospitals of Qom ,2008. Iran J Med Microbiol 2011;5:7-17. [In Persian].
18. Mesgarian M, Zangeneh M, Farhoodi B, Alijani M, Haghani S, Oladi S. Evaluation of patients' characteristics by diagnosing nosocomial infections and its relationship with the rate of antibiotic resistance in Amir Al-Momenin Hospital. iau-tmuj [Internet]. 2021 Jun 1;31(2):241-50. Available from: http://tmuj.iautmu.ac.ir/article-1-1762-en.html [DOI:10.52547/iau.31.2.241]
19. Darvishnia D, Najafi N, Davoudi A, Jafari A, Mirzakhani M. Clinical, Laboratory and Microbiological Characteristics of Patients with Nosocomial Infections Admitted to Sari Fatemeh Zahra Heart Hospital, 2018-2019. J Maz Univ Med Sci. 2022;32(210):108-15.
20. Heydarpour F, Rahmani Y, Heydarpour B, Asadmobini A. Nosocomial infections and antibiotic resistance pattern in open-heart surgery patients at Imam Ali Hospital in Kermanshah, Iran. GMS Hyg Infect Control 2017; 12: Doc07.
21. Sohrabi M, Khosravi A, Zolfaghari P, Sarrafha J. Evaluation of Nosocomial Infections in Imam Hossein(as) Hospital of Shahrood, 2005. Journal of Birjand University of Medical Sciences. 2009;16(3):33- 9.
22. Ghanbari F, Ghajavand H, Behshod P, Ghanbari N, Khademi F. Prevalence of Hospital-Acquired Infections in Hospitalized Patients in Different wards of Shariati Hospital of Isfahan, 2014. Journal of Health. 2018;8(5):511-7.[In Persian].
23. rahmanian v, shakeri h, shakeri m, rahmanian k, rahimi m. Epidemiology of nosocomial infections in patientsadmitted in hospitals Jahrom -2016. Pars of Jahrom University of Medical Sciences. 2017;15(1):57-66. [DOI:10.29252/jmj.15.1.57]
24. Alp E, Cevahir F, Ersoy S, Guney A. Incidence and economic burden of prosthetic joint infections in a university hospital: a report from a middle-income country. Journal of infection and public health. 2016;9(4):494-8. [DOI:10.1016/j.jiph.2015.12.014] [PMID]
25. Hormozi SF, Vasei N, Aminianfar M, Darvishi M, Saeedi AA. Antibiotic resistance in patients suffering from nosocomial infections in Besat Hospital. Eur J Transl Myol 2018; 28(3): 7594. [DOI:10.4081/ejtm.2018.7594] [PMID] []
26. Davoudi Badabi A, Khorashadizadeh H, Aarabi M, Alian S, Ghafari R, Habibi V, etal. Risk Factors for Infection following Coronary Artery Bypass. J Mazandaran Univ Med Sci 2015; 25(131): 79-86 (Persian).
27. Amini M, Sanjari L, Vaseii M, Olumi S. Nosocomial Infections and Related Factors in the Intensive Care Unit (ICU) of Shahid Mostafa Khomeini Hospital Based on System. Annals of Military and Health Sciences Research 2009;7:9-14.
28. Farzanpoor F, rabiee mohammad hasan, Fattahi mojtaba. The study of the prevalence of nosocomial infections in Vasei Hospital of Sabzevar during 2009-2013. J Sabzevar Univ Med Sci [Internet]. 2018;25(2):251-8. Available from: http://jsums.sinaweb.net/article_1064.html
29. Akbari M, Rahim nezhad R, Boronsi A, Ghahremanlo H. The prevalence of nosocomial infections in the ICU of Imam Reza (AS) Urmia city and provide appropriate solutions based on international standards to prevent. 2012; 23(6): 591-596. [in Persian].
30. Ghorbani F, Avaze A, Mohamadi F. Nosocomial infection and factors associated with Ayatollah Mousavi Hospital, Zanjan years 1389. Journal of Infectious Diseases and Tropical Medicine. 2014; 19(66): 15-18. [in Persian].
31. Korol E, Johnston K, Waser N, Sifakis F, Jafri HS, Lo M, et al. A systematic review of risk factors associated with surgical site infections among surgical patients. PLoS One. 2013; 8(12):e83743. [DOI:10.1371/journal.pone.0083743] [PMID] []
32. Ding JG, Sun QF, Li KC, Zheng MH, Miao XH, Ni W, et al. Retrospective analysis of nosocomial infections in the intensive care unit of a tertiary hospital in china during 2003 and 2007. BMC Infect Dis. 2009; 9: 115. [DOI:10.1186/1471-2334-9-115] [PMID] []
33. Caterino JM, Leininger R, Kline DM, Southerland LT, Khaliqdina S, Baugh CW, et al. Accuracy of current diagnostic criteria for acute bacterial infection in older adults in the emergency department. J Am Geriatr Soc. 2017; 65(8):1802-9. [DOI:10.1111/jgs.14912] [PMID] []
34. Mosadeghrad AM, Afshari M, Isfahani P. Prevalence of Nosocomial Infection in Iranian Hospitals: A Systematic Review and Meta- Analysis. irje [Internet]. 2021 Mar 1;16(4):352-62. Available from: http://irje.tums.ac.ir/article-1-6871-fa.html
35. Rahmanian V, Shakeri H, Shakeri M, Rahmanian K, Rahimi M. Epidemiology of nosocomial infections in patients admitted to hospitals in Jahrom -2016. Pars Journal of Medical Sciences.2017; 15: 57-66. [DOI:10.29252/jmj.15.1.57]
36. Bijari B, Abbasi A, Hemati M, Karabi K. Nosocomial infections and related factors in southern khorasan hospitals. Iran J Med Microbiol. 2014; 8: 69-73.[In persian].
37. Aboysani-Bahramizadeh Kh, Sajjadi R, Eds. The study of Relative Frequency of Nosocomial Urinary Tract Infections in Birjand Imam Reza Hospital. Birjand: Birjand Uni Med Sci; 2000.
38. Oncul O, Oksuz S, Acar A, Ulkur E, Turhan V, Uygur F, et al. Nosocomial infection characteristics in a burn intensive care unit: analysis of an eleven-year active surveillance. Burns 2014;40:835-41. [DOI:10.1016/j.burns.2013.11.003] [PMID]
39. Razine R, Azzouzi A, Barkat A, Khoudri I, Hassouni F, Charif chefchaouni A, et al. Prevalence of hospital-acquired infection in the university medical center of Rabat, Morocco. International Archives of Medicin. 2012; 5(26): 2-8. [in Persian]. [DOI:10.1186/1755-7682-5-26] [PMID] []
40. Deborah Friedman N, Kaye S, Stout E, McGarry A, Trivette L, Briggs P, et al. Health care-associated bloodstream infection in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med. 2002; 137: 791-797. [DOI:10.7326/0003-4819-137-10-200211190-00007] [PMID]
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