Showing 2 results for Preeclampsia
Bita Badehnoosh, Ramin Tajbakhsh, Kourosh Kabir, Kiarash Azadi,
Volume 10, Issue 2 (5-2021)
Abstract
Introduction:Preeclampsia is a serious, inflammatory-mediated hypertensive disorder of pregnancy affecting approximately 8% of all pregnancies. Based on recent studies, women with vitamin D deficiency may have an increased risk of developing preeclampsia. The aim of the study was to evaluate the vitamin D and CRP levels and explore the role and correlation between each other and also occurrence of preeclampsia.
Material and methods:55 preeclamptic women and 55 healthy pregnant women were selected from Kamali hospital in karaj, Iran. 6 ml of venous blood sample was collected from each pregnant woman and the serum 25-OH-D and CRP levels were measured by ELISA which reported in ng/mL and mg/dL, respectively. Data were analyzed by independent t-test, Mann-Whitney U test, Chi square and logistic regression.
Results:Preeclamptic women (n=55) were noted to have decreased total 25-OH-D and elevated CRP levels relative to healthy control women (n=55; P<0.001). This difference in vitamin D deficiency remained significant after adjustment for maternal age and BMI [odds ratio (OR) = 12.54, confidence interval (CI) = 1.03–154.95, P=0.047].
Conclusion: These results showed that vitamin D deficiency and abnormal inflammatory status have a statistically significant relationship with preeclampsia and support the hypothesis that vitamin D deficiency may be a risk factor for preeclampsia in the context of an inflammatory condition.
Marzieh Alipour, Khalil Khashei Varnamkhasti, Masumeh Panahi ,
Volume 11, Issue 3 (7-2022)
Abstract
Background: Preeclampsia is a condition of placental pathogenesis, which divided into mild and severe forms, based on the severity of hypertension and proteinuria. Severe type of the disease with HELLP syndrome and neurological symptoms such as seizures play a very important role in maternal complications. Cerebral Venous Thrombosis with incidence of 11.6 per 100,000 deliveries per year, as a rare cerebrovascular disease, can occur as a result of pregnancy-related changes in coagulation state and vascular endothelial damage and be the cause of the life-threatening risks of the preeclamptic mother.
Case Presentation: The patient is a 22-year-old, gravida 1 (33 weeks) woman, with no history of underlying disease, who following the initial seizure and without consciousness, was transferred by the 115th Emergency Department to the triage unit of Valiasr Hospital in Kazerun. Due to repeated recurrent seizures during the 20-minute transmission and the results of test based on HELLP Syndrome, she immediately undergoing a cesarean section. Subsequently, the results of the CAT-SCAN request confirmed the occurrence of cerebral venous thrombosis in the mother. The infant was discharged because of the absence of respiratory disorder and regularity of heart rate. Six-week postpartum follow-up showed maternal recovery.
