Showing 5 results for Arian
1 A. Dehghan, 2 S. , 3 R. Memarian,
Volume 2, Issue 2 (4-2013)
Abstract
Background: Multiple Sclerosis As a chronic disease for some reasons including sudden attack, occur in young Ages, no prognosis and definitive cure causes stress, anxiety and depression in patients. It seems that the more we know the extent of stress, anxiety and depression of patients the more we can control the symptoms. This study was to examine the Abundance of stress, anxiety and depression in Multiple Sclerosis Patients.
Materials and Methods: A cross sectional- descriptive study was conducted using convenient sampling to recruit 110 patients suffering from MS. Data collection tool was DASS 21 questionnaire. Descriptive statistics, chi-square test and Correlation coefficient were used to analysis the data.
Results: Based on the findings Suffer 46.4% Multiple Sclerosis Patients from severe stress, 19.2% of severe anxiety and 29.2% of severe depression. Results of spearman Correlation coefficient showed a significant relationship between the stress, anxiety and depression with Expanded Disability Status and duration of disease (P<0.05). So chi-square test showed a significant relationship between the stress, anxiety and depression with Hospitalizations (P<0.05).
Conclusion: The findings of this research revealed high stress, anxiety and depression in Multiple Sclerosis Patients that can jeopardize their health. Hence the providing appropriate education for coping and adapting with the symptoms in Multiple Sclerosis Patients seems to be necessary.
Enayat Kalantar, Arghavan Etebarian, Seyed Mahmood Amin Marashi, Koroush Kabir, Aboozar Moradi, Atefe Shamosi, Tahere Sheshpari,
Volume 8, Issue 3 (8-2019)
Abstract
Background and aim: Chronic periodontitis has been defined as an infectious disease resulting in inflammation within the dental supporting tissue, progressive attachment loss and bone resorption. Nowadays, with increasing microbial resistance, bacterial therapy is an alternative to prevent inflammatory diseases of the oral cavity, which regulates oral microbiota and eliminating pathogenic bacteria. The aim of this study was to identify oral Lactobacillus species and in patients with periodontitis and healthy individuals.
Materials & Methods: Use of specific culture medium and restriction fragment-length polymorphism (RFLP) analysis was applied to characterize oral lactobacillus in oral cavity samples (saliva, tongue, gingival plaque) from 59 healthy subjects and 59 patients with chronic periodontitis. The 16srDNA genes of lactobacillus .spp in samples were amplified by PCR with universal primers. Sequencing performed to confirm the species.
Results: Out Of 354 examined isolates, 254 isolates were positive for Lactobacillus based on culture and PCR results. From obtained strain cutting patterns analysis of the oral lactobacillus community, were aggregated into ten different species. L.paracasei, L.fermentumin patient and L.casei, L.plantarum were the most predominant species in control groups.
Conclusion: The frequency of Lactobacillus in patients with periodontitis was significantly reduced comparing to the control group, especially in gingival plaque samples. The difference in the frequency of isolated lactobacillus in the total sample of patients was 8% less than control subjects. There is increasing evidence that the use of existing lactobacillus strains can prevent chronic periodontitis. These probiotic candidates can be selected for the purpose of bacteriotherapy, dairy manufacture and pharmaceutical use.
Hossein Zolfagharian, Sima Khalilifard Borojeni, Mahdi Babaie,
Volume 9, Issue 4 (Autumn 2020)
Abstract
Background: In recent years, the number of people with cancer has increased. For this reason, different drugs have been suggested for the treatment of cancer, but none of them has resulted in complete remission. Many bio-toxins are biologically active compounds with anticancer activity. In the meantime, bee venom (BV) has a potent anti cancer and tumor effects. The aim of present study is evaluation of BV anticancer effects on breast cancer cell line (MDA-MB-231).
Methods: Crude bee venom was obtained from Apis mellifera and the amount of its protein was determined. MDA-MB-231 cancer cell line was cultured and then the cells were exposed to 1.56, 3.125, 3.25, 6.25, 12.5, 25 and 50 µg/ml of bee venom for 24 and 48 h, respectively. The morphology and apoptosis were evaluated and cell viability was determinedby MTT assay.
Results: MTT assay showed that BV at concentration 6.25 µg/ml for MDA-MB-231 killed 50% of cells (p<0.05). Morphological analysis and the obtained data indicated that cell death caused by BV was induced apoptosis.
Conclusion: Findings indicated that BV have anticancer effects and with further investigation, it can be used in production of anticancer drugs.
Ali Shahini, Mahnaz Arian,
Volume 10, Issue 3 (Summer 2021)
Abstract
The patient is a 38-year-old woman with a complaint of fever, chills, and abdominal pain for 10 days. She had a history of recent abortion with nausea and vomiting and oral intolerance. She was admitted with a diagnosis of abdominal infections. Abdominal and pelvic CT scan were performed by contrast injection.
Morteza Safarian, Kumarss Amini,
Volume 10, Issue 4 (Autumn 2021)
Abstract
Aim and objective: Proteus mirabilis is one of the most common causes of urinary tract infections (UTI) and bacteremia. The aim of this study was to evaluate the antibiotic susceptibility of P. mirabilis strains isolated from urinary tract.
Material and method: In this cross-sectional study, 60 Proteus mirabilis were obtained from the human urine samples. Detection of strains were performed by standard microbiological and biochemical tests. Antimicrobial susceptibility test was performed by disk diffusion test according to the clinical laboratory sard institute test (CLSI) on the muller hinton agar. Then, multiplex-PCR was achieved for determination flaA and urea genes in the strains by specific oligonucleotides primers.
Results: All the isolates of P. mirabilis in polymerase chain reaction were showed that flaA and urea genes. The resistance rate was obtained to tobramycin and kanamycin (53%), gentamicin (46%), amikacin (40%), cefotaxime (36%) and ceftriaxone (31%).
Conclusion: According to this study it’s necessary to determine the antibiotic susceptibility of Proteus mirabilis isolated from urinary tract infections in order to provide proper treatment, this will prevent their dissemination and reduce the risk of urinary tract infection complication.
