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The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat
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Razieh Dehghanian   , Seyyed Ebrahim Hosseini  , Esfandiar Sharifi , Davood Moghadamnia |
| Associated Professor in Animal Physiology, Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran , ebrahim.hossini@yahoo.com |
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Abstract: (3330 Views) |
Background: Taraxacum Officinale is a medical plant with antioxidant benefit effects. The aim of the present study is to evaluate the effect of Taraxacum Officinale alcoholic extract on serum thyroid hormone levels in adult male rat.
Material and Methods: In this experimental study,45 adult male wistar rats were approximate average weight body of 200-250 gr were divided in to 5 groups of 9. Control ,sham ,and three experimental groups which received 50,100,150mg/kg of Taraxacum Officinale alcoholic extract by used gavage method. After this period (14 days) blood sample were collected and after measuring the amount of thyroid hormones of T3,T4,TSH hormones, data were analyzed by using SPSS software , ANOVA and t-test.
Results: The results showed that body weight average and serum level of T4 hormone in receiving maximum dose of Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group. T3 serum level in experimental groups receiving Taraxacum Officinale alcoholic extract didn't show any significant difference comparing to control group. TSH serum level in experimental groups receiving Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group (p<0.05).
Conclusion: The Taraxacum Officinale alcoholic extract reduced serum thyroid hormone levels in adult male rat. |
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| Keywords: Taraxacum Officinale, T3, T4, TSH, Adult Male Rat |
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Full-Text [PDF 184 kb]
(1813 Downloads)
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Type of Study: case report |
Subject:
Special
Received: 2018/10/01 | Accepted: 2018/10/01 | Published: 2018/10/01
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