[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 9, Issue 1 (2-2020) ::
aumj 2020, 9(1): 31-36 Back to browse issues page
Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis
Ahmadreza Mirzaei, Mahboobeh Mehrabani, Zohreh Khodaii, Hamid Mirshamsi, Nasrin Rafieian
Dietary Supplements and Probiotics Research Center, Alborz University of Medical Sciences, Karaj, Iran Department of Oral Medicine, Faculty of Dentistry, Alborz University of Medical Sciences, Karaj, Iran , rafieiann@yahoo.com
Abstract:   (1060 Views)
Background: Periodontal diseases in smokers are 2.6 to 6 times higher than non-smokers and their response to treatment is much lower. Reducing levels of antioxidants and consequently increasing oxidative damage in the pathogenesis of periodontitis is effective. Regarding the importance of free radicals in the pathogenesis of periodontal diseases, the aim of this study was to investigate the effect of cigarette on the oxidative and antioxidant status of saliva in chronic periodontitis patients and compare it with healthy controls.
Methods: In this case-control study, 20 patients with chronic cigarette smoking periodontitis, 20 patients with non-smoking chronic periodontitis and 20 healthy individuals who had no history of periodontitis and smoking, were among those referring to dental clinics and clinics of Karaj were chosen. Uninstivated saliva was collected and salivary total antioxidant capacity was measured using a kit in saliva. Statistical analysis was performed using ANOVA.
Results: Total antioxidant capacity of saliva in smoker periodontitis and non-smoker periodontitis was significantly (P <0.05) less than normal Persons.
Conclusion: Based on the results of this study, chronic periodontitis reduces the total antioxidant capacity of saliva, on the one hand, due to the increased production of oxidants in inflammatory responses to this disease, and, on the other hand, the presence of compounds such as nicotine cigarette that disturbs the chain Respiratory mitochondria and increased oxidants.
Keywords: Periodontitis, Cigarette, Total Antioxidant Capacity, FRAP
Full-Text [PDF 246 kb]   (314 Downloads)    
Type of Study: Research | Subject: Special
Received: 2020/03/04 | Accepted: 2020/03/04 | Published: 2020/03/04
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mirzaei A, Mehrabani M, Khodaii Z, Mirshamsi H, Rafieian N. Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis. aumj. 2020; 9 (1) :31-36
URL: http://aums.abzums.ac.ir/article-1-1057-en.html

Volume 9, Issue 1 (2-2020) Back to browse issues page
نشریه دانشگاه علوم پزشکی البرز Alborz University Medical Journal
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4269